Important Safety Information (GLP-1 medicines)
Boxed warning: risk of thyroid C-cell tumors
Semaglutide and tirzepatide caused thyroid C-cell tumors in rodents. It is not known whether they cause these tumors, including medullary thyroid carcinoma (MTC), in people. Do not use if you or a family member has had MTC, or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Tell your clinician right away about a neck lump, hoarseness, trouble swallowing or shortness of breath.
Common side effects include nausea, diarrhea, vomiting, constipation and stomach pain. Serious side effects can include pancreatitis, gallbladder problems, low blood sugar and kidney problems. Seek care right away for severe stomach pain that does not go away.
Not for use during pregnancy. Results vary. A licensed clinician decides whether a GLP-1 medicine is appropriate for you. Compounded medications are not FDA-approved. This page describes a fictional sample practice and is not medical advice.